STUDY OF LYSERGIC ACID DIETHYLAMIDE AS AN ANALGESIC AGENT.

An ideal analgesic agent has not yet been discovered. The criteria for such an analgesic would be: to give relief from pain, offer no impairment of the sensorium, maintain interest in life, have no unpleasant side effects, and be long lasting and effective in a high percent of cases. In the quest for such a remedy, we explored the analgesic action of lysergic acid diethylamide (LSD- 25), an ergot derivative which has a number of psychic effects in humans. This is a preliminary report on the analgesic actions of LSD-25.